Data & Safety Monitoring Board

A Data & Safety Monitoring Board (DSMB) is an independent body of clinicians, statisticians and individuals from other disciplines whose task is to review accumulating trial data and make recommendations to the Trial Steering Committee concerning the conduct of the trial and whether the trial should continue in its current form. The primary objective of a DSMB is to ensure that the trial remains appropriate and safe for individuals who have been, or are still to be, enrolled. Other responsibilities include monitoring trial progress and overall quality of trial conduct.

Members of current and past DSMBs and the trials they monitored are as follows.

Current DSMB
IMPROVE-CKD; CKD-FIX; TEACH-PD and BEST-Fluids Trials
Members
Bruce Neil (Chair)
Andrew Forbes
David Wheeler
Christoph Wanner

PHOSPHATE Trial
Members
Christoph Warner
Andrew Forbes
Anthony Keech
Bryan Kestenbaum

Current Safety Monitoring Committee
NAVKIDS2 Trial
Members
Tom Snelling (Chair)
David Issacs
Nicholas Larkin

GOAL Trial
Members
Suetonia Palmer (Chair)
Sabine Braat
Vasi Naganathan
Elizabeth Ryan 

Past DSMB
HERO; FAVOURED and HONEYPOT Trials
Members
Andrew Tonkin (Chair)
Andrew Forbes
Adeera Levin
David Wheeler

BLOCADE Trial
Members
Adeera Levin (Chair)
Andrew Martin
David Hare
David Wheeler